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Spironolactone is used in combination with other medicines to treat high blood pressure (hypertension) and heart failure. Lowering blood pressure can reduce the risk of strokes and heart attacks. Spironolactone is also used to lessen the need for hospitalization for heart failure. What is spironolactone most commonly used for? Spironolactone is used to treat build-up of fluid in your body (oedema) caused by: heart failure. liver disease – it treats build-up of fluid in your abdomen, called ascites. kidney disease – it treats a condition that causes your kidneys to leak large amounts of protein into your pee, called nephrotic syndrome.We accept bulk orders contact 09453742525